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Volume 3, Issue 12

thrombophlebitis: a nosocomial multidrug-resistant disease? Open Access

Abstract

is a non- commensal bacterium with a wide range of pathogenicity. The identification of multidrug-resistant (MDR) is concerning because drug susceptibility testing is not usually performed in microbiology laboratories. There is no consensus yet on the treatment of septic thrombophlebitis in this situation.

We report here the first case of a quinquagenarian patient with a history of AIDS and fungic endocarditis, who was diagnosed with a nosocomial thrombophlebitis in the right jugular vein caused by . Bitherapy with daptomycin for 12 days and linezolid for 23 days was combined with a therapeutic anticoagulant. The follow-up included weekly cervical ultrasound controls. The efficiency of the treatment and the stability of the lesions allowed us to alleviate the medication with a prophylactic dose of anticoagulant. The patient was discharged from hospital and showed no signs of recurrence after 12 months.

The lack of consensus relative to the management of septic thrombophlebitis precludes the validation of a specific treatment for the condition. Our results suggest that a combination that includes removal of the medical device is needed. A total of 6 weeks of antibiotherapy should be applied, starting with 2 weeks of vancomycin or a combination of antibiotitherapy with daptomycin in order to reduce the bacterial load and avoid resistance. Six weeks of anticoagulation therapy is effective.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): Corynebacterium , multidrug resistance and septic thrombophlebitis
© 2021 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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2021-12-17
2024-12-07
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Corynebacterium striatum thrombophlebitis: a nosocomial multidrug-resistant disease?
Access Microbiology 3, 000307 (2021); https://doi.org/10.1099/acmi.0.000307
/content/journal/acmi/10.1099/acmi.0.000307
/content/journal/acmi/10.1099/acmi.0.000307
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