is a rare cause of endocarditis and is particularly unusual in non-immunosuppressed hosts. It is associated with animal bites, particularly those from dogs. This case describes a healthy 59-year-old woman, with no identifiable risk factors or dog bite history, who presented with fever of unknown origin. Echocardiography demonstrated an aortic valve mass and root abscess, in keeping with endocarditis, requiring urgent valve replacement surgery. Eight sets of blood cultures were drawn in total; after prolonged incubation, one set grew . There was initial uncertainty over this being the causative organism, given the lack of immunosuppression or dog bite history, but 16S PCR of the valve identified the same organism, permitting targeted treatment. This case highlights the value of valve 16S PCR as a diagnostic tool in endocarditis.

Keyword(s): 16s PCR , Capnocytophaga and endocarditis
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.

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  1. Hayani O, Lyall AJ, Higginson BT, Burwash IG. Man’s best friend? Infective endocarditis due to Capnocytophaga canimorsus. Can J Cardiol 2009; 25:e130–e132 [View Article]
    [Google Scholar]
  2. Butler T. Capnocytophaga canimorsus: an emerging cause of sepsis, meningitis, and post-splenectomy infection after dog bites. Eur J Clin Microbiol Infect Dis 2015; 34:1271–1280 [View Article][PubMed]
    [Google Scholar]
  3. Sakai J, Imanaka K, Kodana M. Infective endocarditis caused by Capnocytophaga canimorsus; a case report. BMC Infect Dis 2019; 19:927 [View Article][PubMed]
    [Google Scholar]
  4. Risum M, Ellekvist P. Capnocytophaga canimorsus-meningitis diagnosticeret ved hjælp af 16S rRNA-analyse [Capnocytophaga canimorsus meningitis diagnosed by means of a 16S rRNA analysis].. Ugeskr Laeger 2012; 174:280–281
    [Google Scholar]
  5. Beernink TM, Wever PC, Hermans MH, Bartholomeus MG. Capnocytophaga canimorsus meningitis diagnosed by 16S rRNA PCR. Pract Neurol 2016; 16:136–138 [View Article][PubMed]
    [Google Scholar]

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