@article{mbs:/content/journal/acmi/10.1099/acmi.0.000233, author = "Karczewski, Daniel and Müllner, Maximilian and Perka, Carsten and Müller, Michael", title = "Clostridium difficile septic arthritis and periprosthetic joint infection in a patient with acute lymphoblastic leukaemia, T-/B-lymphocytopenia and hypogammaglobulinemia – a case report and review of the literature", journal= "Access Microbiology", year = "2021", volume = "3", number = "5", pages = "", doi = "https://doi.org/10.1099/acmi.0.000233", url = "https://www.microbiologyresearch.org/content/journal/acmi/10.1099/acmi.0.000233", publisher = "Microbiology Society", issn = "2516-8290", type = "Journal Article", keywords = "periprosthetic joint infection", keywords = "septic arthritis", keywords = "ALL", keywords = "hypogammaglobulinemia", keywords = "Clostridium difficile", eid = "000233", abstract = "To the best of our knowledge, we report the first Clostridium difficile infection in a native hip joint with subsequent prosthetic joint infection in a patient at a state of hypogammaglobulinemia. The infection developed following chemotherapy for B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). After chemotherapy, hip arthroplasty was performed for destructive septic arthritis. However, infection in the hip persisted with several failing revisions for more than 3 years, until ultimately hypogammaglobulinemia and T-/B-lymphocytopenia were diagnosed, and supplementation with i.v. immunoglobulins was able to achieve infection control.", }