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Volume 3, Issue 1

is a rare cause of infected chronic contained rupture of abdominal aortic aneurysm Open Access

Abstract

is an anaerobic, partially acid-fast, Gram-positive bacillus associated with abscess formation. We present the case of a 70-year-old male with chronic contained rupture of abdominal aortic aneurysm (CCR-AAA) complicated by intra-abdominal abscess formation. An abdominal computed tomography scan revealed a rim-enhancing retroperitoneal collection tracking into the subcutaneous layer of the left flank and buttock, suggestive of CCR-AAA with infected haematoma. He underwent ultrasound-guided needle aspiration of the intra-abdominal collection. Conventional culture techniques failed to isolate , and the diagnosis was only confirmed by means of 16S rRNA PCR. The patient underwent branched endovascular repair of his aneurysm, and was commenced on treatment with co-amoxiclav, resulting in significant reduction in the size of the infected collection. This is only the second reported case of infection with in the UK, and the first reported case of this organism causing infected CCR-AAA.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): 16S rRNA PCR , abdominal aortic aneurysm , co-amoxiclav , fastidious , Gram-positive bacillus , intra-abdominal infection , Lawsonella clevelandensis and partially acid fast
© 2021 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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/content/journal/acmi/10.1099/acmi.0.000183
2020-11-25
2024-04-25
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References

  1. Bell ME, Bernard KA, Harrington SM, Patel NB, Tucker T-A et al. Lawsonella clevelandensis gen. nov., sp. nov., a new member of the suborder Corynebacterineae isolated from human abscesses. Int J Syst Evol Microbiol 2016; 66:2929–2935 [View Article][PubMed]
     [Google Scholar]
  2. Harrington SM, Bell M, Bernard K, Lagacé-Wiens P, Schuetz AN et al. Novel fastidious, partially acid-fast, anaerobic Gram-positive Bacillus associated with abscess formation and recovered from multiple medical centers. J Clin Microbiol 2013; 51:3903–3907 [View Article][PubMed]
     [Google Scholar]
  3. Navas ME, Jump R, Canaday DH, Wnek MD, SenGupta DJ et al. Can anaerobes be acid fast? A novel, clinically relevant acid fast anaerobe. JMM Case Rep 2016; 3:e005036 [View Article][PubMed]
     [Google Scholar]
  4. Chudy-Onwugaje K, Vandermeer F, Quezada S. Mimicking Abdominal Tuberculosis: Abdominal Abscess Caused by Lawsonella clevelandensis in Inflammatory Bowel Disease. Clin Gastroenterol Hepatol 2019; 17:e92 [View Article][PubMed]
     [Google Scholar]
  5. Kumaria A, Lucas EK, Crusz SA, Howarth SPS, Cartmill M. Lawsonella clevelandensis causing spinal subdural empyema. Br J Neurosurg 201813 [View Article][PubMed]
     [Google Scholar]
  6. Favila Menezes M, Sousa MJ, Paixão P, Atouguia J, Negreiros I et al. Lawsonella clevelandensis as the causative agent of a breast abscess. IDCases 2018; 12:95–96 [View Article][PubMed]
     [Google Scholar]
  7. Alshafei A, Kamal D. Chronic contained abdominal aortic aneurysm rupture mimicking vertebral spondylodiscitis: a case report. Ann Vasc Dis 2015; 8:113–115 [View Article][PubMed]
     [Google Scholar]
  8. Harris KA, Hartley JC. Development of broad-range 16S rRNA PCR for use in the routine diagnostic clinical microbiology service. J Med Microbiol 2003; 52:685–691 [View Article][PubMed]
     [Google Scholar]
  9. Harris KA, Yam T, Jalili S, Williams OM, Alshafi K et al. Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rRNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and ireland hospitals. Eur J Clin Microbiol Infect Dis 2014; 33:2061–2066 [View Article][PubMed]
     [Google Scholar]
  10. Nicholson AC, Bell M, Humrighouse BW, McQuiston JR. Complete genome sequences for two strains of a novel fastidious, partially acid-fast, Gram-positive Corynebacterineae bacterium, derived from human clinical samples. Genome Announc 2015; 3:e01462-15 [View Article][PubMed]
     [Google Scholar]
  11. Sörelius K, Wanhainen A, Furebring M, Björck M, Gillgren P et al. Swedish collaborator group for mycotic abdominal aortic Aneurysms.Nationwide study of the treatment of mycotic abdominal aortic aneurysms comparing open and endovascular repair. American heart association journals 2016
     [Google Scholar]
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Lawsonella clevelandensis is a rare cause of infected chronic contained rupture of abdominal aortic aneurysm
Access Microbiology 3, 000183 (2021); https://doi.org/10.1099/acmi.0.000183
/content/journal/acmi/10.1099/acmi.0.000183
/content/journal/acmi/10.1099/acmi.0.000183
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