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Volume 2, Issue 9

Pleural empyema due to in a patient with bronchogenic carcinoma: the first case report from a cancer hospital in Egypt Open Access

Abstract

species are motile, Gram-negative facultative anaerobic bacilli, which belong to the family . The most common clinical presentations of infection are gastroenteritis and enteric fever. Detection of organisms in empyema is very rare.

We report the case of a 66-year-old female patient with bronchogenic carcinoma who developed empyema, and was identified from the culture of pleural fluid. After antimicrobial therapy and other therapeutic measures, including the insertion of an intercostal tube, oxygen supplementation, frequent suction of respiratory secretions, and chest physiotherapy, the patient's condition improved. To the best of our knowledge, this is the first case to be reported in Egypt.

Our case sheds light on the role of in immunocompromised patients in general and cancer patients in specific. We recommend further study of this role, since it may lead to a better understanding of the pathogenicity of this organism in these patients.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): bronchogenic carcinoma , cancer , empyema and Salmonella
© 2020 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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2020-07-15
2024-04-25
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References

  1. Pathmanathan S, Welagedara S, Dorrington P, Sharma S. Salmonella empyema: a case report. Pneumonia 2015; 6:120–124 [View Article][PubMed]
     [Google Scholar]
  2. Ryan MP, O'Dwyer J, Adley CC. Evaluation of the complex nomenclature of the clinically and veterinary significant pathogen Salmonella . Biomed Res Int 2017; 2017:3782182 [View Article][PubMed]
     [Google Scholar]
  3. Rim MS, Park CM, Ko KH, Lim SC, Park KO et al. Pleural empyema due to Salmonella: a case report. Korean J Intern Med 2000; 15:138–141 [View Article][PubMed]
     [Google Scholar]
  4. Mandell GL, Bennett JE, Dolin R. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 2nd edn. Churchil Livingstone Elsevier; 2010
     [Google Scholar]
  5. Crum-Cianflone NF. Salmonellosis and the gastrointestinal tract: more than just peanut butter. Curr Gastroenterol Rep 2008; 10:424–431 [View Article][PubMed]
     [Google Scholar]
  6. Zubrod CG, Schneiderman M, Frei E, Brindley C, Lennard Gold G et al. Appraisal of methods for the study of chemotherapy of cancer in man: comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide. J Chronic Dis 1960; 11:7–33 [View Article]
     [Google Scholar]
  7. Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009; 45:228–247 [View Article][PubMed]
     [Google Scholar]
  8. WHO Laboratory Protocol “Biochemical Identification of Salmonella and Shigella Using an Abbreviated Panel of Tests. Avaialbe at http://antimicrobialresistance.dk/CustomerData/Files/Folders/2-newsletter-pdf/20_07-gfn-biochem-v002-final-16oct2015.pdf. (Accessed 26 May 2020).
  9. Morka K, Bystroń J, Bania J, Korzeniowska-Kowal A, Korzekwa K et al. Identification of Yersinia enterocolitica isolates from humans, pigs and wild boars by MALDI TOF MS. BMC Microbiol 2018; 18:86 [View Article][PubMed]
     [Google Scholar]
  10. Xaplanteri P, Assimakopoulos SF, Karachalios K, Siagris D, Lekkou A et al. Pleural empyema due to Salmonella enterica serovar Enteritidis in an immunocompetent elderly patient: a case report. JMM Case Rep 2016; 3:e005051 [View Article][PubMed]
     [Google Scholar]
  11. Whimbey E, Gold JW, Polsky B, Dryjanski J, Hawkins C et al. Bacteremia and fungemia in patients with the acquired immunodeficiency syndrome. Ann Intern Med 1986; 104:511–514 [View Article][PubMed]
     [Google Scholar]
  12. Levine WC, Buehler JW, Bean NH, Tauxe RV et al. Epidemiology of nontyphoidal Salmonella bacteremia during the human immunodeficiency virus epidemic. J Infect Dis 1991; 164:81–87 [View Article]
     [Google Scholar]
  13. Sperber SJ, Schleupner CJ. Salmonellosis during infection with human immunodeficiency virus. Clin Infect Dis 1987; 9:925–934 [View Article]
     [Google Scholar]
  14. Fischl MA, Dickinson GM, Sinave C, Pitchenik AE, Cleary TJ et al. Salmonella bacteremia as manifestation of acquired immunodeficiency syndrome; 1986; 146113–115
  15. Kaye D, Gill FA, Hook EW. Factors influencing host resistance to Salmonella infections. Am J Med Sci 1967; 254:205–215 [View Article]
     [Google Scholar]
  16. Guerrant RL, Van Gilder T, Steiner TS, Thielman NM, Slutsker L et al. Practice guidelines for the management of infectious diarrhea. Clin Infect Dis 2001; 32:331–351 [View Article][PubMed]
     [Google Scholar]
  17. Hung C-C, Hung M-N, Hsueh P-R, Chang S-Y, Chen M-Y et al. Risk of recurrent nontyphoid Salmonella bacteremia in HIV-infected patients in the era of highly active antiretroviral therapy and an increasing trend of fluoroquinolone resistance. Clin Infect Dis 2007; 45:e60–e67 [View Article][PubMed]
     [Google Scholar]
  18. Glynn MK, Reddy V, Hutwagner L, Rabatsky-Ehr T, Shiferaw B et al. Prior antimicrobial agent use increases the risk of sporadic infections with multidrug-resistant Salmonella enterica serotype typhimurium: a FoodNet case-control study, 1996–1997.; 2004; 38S227–S236
  19. Lanaya H, Natarajan A, Komposch K, Li L, Amberg N et al. EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation. Nat Cell Biol 2014; 16:972–981 [View Article][PubMed]
     [Google Scholar]
  20. Chan G, Nogalski MT, Yurochko AD. Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility. Proc Natl Acad Sci U S A 2009; 106:22369–22374 [View Article][PubMed]
     [Google Scholar]
  21. Mahtouk K, Hose D, Rème T, De Vos J, Jourdan M et al. Expression of EGF-family receptors and amphiregulin in multiple myeloma. amphiregulin is a growth factor for myeloma cells. Oncogene 2005; 24:3512–3524 [View Article][PubMed]
     [Google Scholar]
  22. Zaiss DMW, van Loosdregt J, Gorlani A, Bekker CPJ, Gröne A et al. Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor. Immunity 2013; 38:275–284 [View Article][PubMed]
     [Google Scholar]
  23. MacDonald F, Zaiss DMW. The immune system's contribution to the clinical efficacy of EGFR antagonist treatment. Front Pharmacol 2017; 8:575 [View Article][PubMed]
     [Google Scholar]
  24. Dhillon S. Gefitinib: a review of its use in adults with advanced non-small cell lung cancer. Target Oncol 2015; 10:153–170 [View Article][PubMed]
     [Google Scholar]
  25. Wang Y, Wang M, Wang Q, Geng Z, Sun M et al. Incidence and risk of infections associated with EGFR-TKIs in advanced non-small-cell lung cancer: a systematic review and meta-analysis of randomized controlled trials. Oncotarget 2017; 8:29406–29415 [View Article][PubMed]
     [Google Scholar]
  26. Yuasa T, Yamamoto S, Urakami S, Fukui I, Yonese J et al. Denosumab: a new option in the treatment of bone metastases from urological cancers. Onco Targets Ther 2012; 5:221–229 [View Article][PubMed]
     [Google Scholar]
  27. Scagliotti GV, Hirsh V, Siena S, Henry DH, Woll PJ et al. Overall survival improvement in patients with lung cancer and bone metastases treated with denosumab versus zoledronic acid: subgroup analysis from a randomized phase 3 study. J Thorac Oncol 2012; 7:1823–1829 [View Article][PubMed]
     [Google Scholar]
  28. Wong BR, Rho J, Arron J, Robinson E, Orlinick J et al. Trance is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J Biol Chem 1997; 272:25190–25194 [View Article][PubMed]
     [Google Scholar]
  29. Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397:315–323 [View Article][PubMed]
     [Google Scholar]
  30. Afridi FI, Farooqi BJ, Hussain A. Pleural empyema due to Salmonella typhi. J Coll Physicians Surg Pak 2012; 22:803–805
     [Google Scholar]
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Pleural empyema due to Salmonella in a patient with bronchogenic carcinoma: the first case report from a cancer hospital in Egypt
Access Microbiology 2, e000151 (2020); https://doi.org/10.1099/acmi.0.000151
/content/journal/acmi/10.1099/acmi.0.000151
/content/journal/acmi/10.1099/acmi.0.000151
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