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rapidly identified by MALDI-TOF MS. A rare gram-variable agent of bacteraemia. Open Access

Abstract

is an enteric anaerobic, endospore-forming, gram-positive rod with a low GC content that is rarely associated with disease in humans. We present a case of bacteraemia. To the best of our knowledge, this is the second case of bacteraemia in an elderly patient presenting with fever, abdominal pain and bilious emesis. We highlight the Gram stain variability, the lack of visualization of spores and the atypical morphology of the colonies that showed in a polymicrobial presentation that initially appeared to show monomicrobial bacteraemia. The microorganism was rapidly identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). We present a comprehensive literature review of 32 cases of clinical infections by in which we describe, if available, sex, age, clinical symptoms, predisposing conditions, other organisms present in the blood culture, other samples with , identification methodology, treatment and outcome.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): Antimicrobial susceptibility , Bacteraemia , Clostridium ramosum , Erysipelatoclostridium ramosum , Infection and MALDI-TOF MS
© 2020 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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2020-06-15
2024-04-25
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Clostridium ramosum rapidly identified by MALDI-TOF MS. A rare gram-variable agent of bacteraemia.
Access Microbiology 2, e000137 (2020); https://doi.org/10.1099/acmi.0.000137
/content/journal/acmi/10.1099/acmi.0.000137
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