|
Variant names and aliases |
Spike mutations |
Other non-synonymous mutations in genome |
|---|---|---|
|
B.1.1.7 VOC-20DEC-01 aka 20B/501Y.V1 (UK) |
L18F*,†, Δ69–70, Δ144, N501Y, A570D, D614G‡, P681H, T716I, S982A, D1118H |
NSP3 – T183I, A890D, I1412T; NSP6 – Δ106–108; NSP12 – P323L; ORF8 – Q27STOP, R52I, Y73C; N – D3L, S235F |
|
B.1.351 aka 20B/501Y.V2 aka VOC-20DEC-02 (South Africa) |
L18F*, D80A, D215G*, Δ242–244*, R246I*, K417N*, E484K, N501Y, D614G, A701V |
NSP2 – T85I; NSP3 – K837N; NSP5 – K90R; NSP6 – Δ106–108*; NSP12 – P323L; ORF3a – Q57H, S171L; E – P71L; N – T205I |
|
P.1 aka 20B/501Y.V3 aka VOC-21JAN-02 (Japan ex Brazil) |
L18F, T20N§, P26S, D138Y, R190S*, K417T, E484K, N501Y, D614G, H655Y, T1027I |
NSP3 - S370L, K977Q; NSP6 – Δ106–108; NSP12 – P323L; NSP13 – E341D; Orf3a – S253P*; ORF8 – E92K; N –P80R R203K, G204R |
|
A.23.1/E484K aka VUI-21FEB-01 (UK) |
R102I, F157L, V367F, E484K, Q613H, P681R |
NSP3 – L741F; NSP6 – M86I, L98F, M183I; ORF8 – L84S, E92K; N – S202N |
|
B.1.525 aka VUI-21FEB-03 (UK ex West Africa) |
Q52R, A67V*, Δ69–70, Δ144, E484K, D614G, Q677H, F888L |
NSP3 – T1189I; NSP6 – Δ106–108; NSP12 – P323F; E – L21F; M – I82T; ORF6 – Δ2; N – Δ2/D3Y, A12G, T205I |
|
B.1.1.318 aka VUI-21FEB-04 (UK ex West Africa) |
T95I, Δ144, E484K, D614G, P681H, D796H |
NSP1 – Δ85; NSP3 – S126L*, E378V, K1693N; NSP4 – T173I, A446V; NSP5 – T21I; NSP6 Δ106–108; NSP12 – P323L; NSP15 – V320M; NSP16 – A116S*; M – I82T; ORF7b/ORF8 fusion +ORF8 E106STOP; N –R203K, G204R, Δ208/R209G |
|
B.1.324.1/E484K aka VUI-21MAR-01 (UK ex Antigua) |
E484K, S494P, N501Y, D614G, P681H, E1111K |
NSP2 – T85I; NSP3 – T1378P*; NSP4 – T189I, T439M; NSP6 – H11Q; NSP9 – P57S; NSP12 – S6L, P323L; ORF3a – Q57H, ORF8 – 35 bp deletion and frameshift; N – M234I |
|
P.3 aka VUI-21MAR-02 (Philippines) |
Δ141–143, Δ243–244*, Y265C, E484K, N501Y, D614G, P681H, E1092K, H1101Y, V1176F |
NSP3– D736G, S1807F*; NSP4 – D217N*, L438P; NSP6 – D112E; NSP7 – L71F; NSP12 – P323L;NSP13 – L280F*, A368V; ORF8 – K2Q; N – R203K, G204R |
|
B.1.526 (New York) |
L5F, T95I, D253G, E484K* or S477N*, D614G, A701V, |
NSP2 – T85I; NSP3 – V1139I; NSP4 – L438P; NSP6 – L37F, Δ106–108, NSP12 – P323L; NSP13 – Q88H; ORF3a – P42L, Q57H; ORF8 – T11I; N – P199L, M234I |
|
A.27 (Mayotte) |
L18F*, L452R*, N501Y, A653V, H655Y, Q677H*, D796Y, G1219V |
NSP2 – P106L; NSP4 – D217G*; NSP6 – N82S; NSP13 – P77L; ORF3a – V50A, 8nt deletion and frameshift; ORF8 – L84S, del119-120; N – S202N |
|
Cluster 5 (Danish Mink) |
Δ69–70, Y453F, D614G, I692V, M1229I |
NSP1 - Δ85; NSP3 - Δ1264; NSP12 – P323L, T739I; NSP15 – T112I; ORF3a – H182Y; N - S194L, R203K, G204R |
|
*Indicates mutation found in some, but not all variants of this lineage. tbl2fn2†Residues in bold indicate mutations found in multiple variants. tbl2fn3‡Residues in italics indicate substitutions likely present in the ancestral viruses. tbl2fn4§Indicates mutations predicted to result in addition of a new N-linked glycosylation site. |