32-week premature rupture of membranes caused by oropharyngeal microbiota

Alberto Hidalgo-Chicharro; Raquel Abad-Torreblanca; José María Navarro-Marí; José Gutiérrez-Fernández

doi:10.1099/jmmcr.0.005121

Volume 4, Issue 10

Case Report

Open Access

32-week premature rupture of membranes caused by oropharyngeal microbiota

Alberto Hidalgo-Chicharro^1,†, Raquel Abad-Torreblanca², José María Navarro-Marí³ and José Gutiérrez-Fernández^3,4,†
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Affiliations: ¹ Unidad de Gestión Clínica de Obstetricia y Ginecología, Hospital Universitario San Cecilio, Granada, Spain ² Spanish Reference Laboratory for Meningococci, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain ³ Servicio de Microbiología, Hospital Universitario Virgen de las Nieves-ibsGranada, Granada, Spain ⁴ Department of Microbiology, University of Granada-ibsGranada, Granada, Spain
*Correspondence: José Gutiérrez-Fernández, [email protected]

† These authors contributed equally to this work.
Published: 16 October 2017 https://doi.org/10.1099/jmmcr.0.005121

Abstract

Introduction. Preterm premature rupture of membranes (PPROM) usually has a multifactorial etiology that is often unknown, although the most frequently reported cause is infection by group B Streptococcus. Therefore, the etiology of PPROM, although probably infectious, remains unknown in most cases. This case describes a PPROM caused by infection from oropharyngeal microbiota.

Case presentation. We report the case of a 26-yr-old pregnant woman. The gestational age was 32 weeks+5 days. Examinations in the emergency department revealed the release of clear amniotic fluid and a closed multiparous cervix with a length of 22 mm. Endocervical culture evidenced the growth of Staphylococcus aureus, serogroup B Neisseria meningitidis and Haemophilus influenzae.

Conclusion. Preventive antibiotic therapy should consider: opportunistic infections by normal genital microbiota, infections due to sexual activity, opportunist microorganisms derived from oral sex, and the hematogenous spread of oral bacteria.

Received: 04/07/2017
Accepted: 29/09/2017
Published Online: 16/10/2017

Keyword(s): Haemophilus influenzae , molecular characterization , Neisseria meningitidis , premature rupture of membranes , preventive antibiotic therapy and Staphylococcus aureus

This is an open access article under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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Volume 4, Issue 10

Case Report

Open Access

32-week premature rupture of membranes caused by oropharyngeal microbiota

Abstract

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