1887

Abstract

The aim of this study was to characterize the presence of carbapenemase-encoding genes in distinct species of spp. isolated from Brazilian hospitals. Five carbapenem-resistant spp. isolates (two , two and one ) recovered from two distinct hospitals between 2000 and 2016 were included in this study. All of the isolates harboured , which was inserted into In a class 1 integron. Pulsed field gel eletrophoresis analysis showed that both were identical, while the two isolates were considered to be clonally related. In this study, we demonstrated that mobile elements carrying carbapenemase-encoding genes such as In may persist for a long period, allowing their mobilization from to other spp. that are usually susceptible to multiple antimicrobials.

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/content/journal/jmm/10.1099/jmm.0.000732
2018-05-01
2024-03-29
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References

  1. Choi JY, Kim Y, Ko EA, Park YK, Jheong WH et al. Acinetobacter species isolates from a range of environments: species survey and observations of antimicrobial resistance. Diagn Microbiol Infect Dis 2012; 74:177–180 [View Article][PubMed]
    [Google Scholar]
  2. Gundi VA, Dijkshoorn L, Burignat S, Raoult D, La Scola B. Validation of partial rpoB gene sequence analysis for the identification of clinically important and emerging Acinetobacter species. Microbiology 2009; 155:2333–2341 [View Article][PubMed]
    [Google Scholar]
  3. Cayô R, Rodrigues-Costa F, Matos AP, Carvalhaes CG, Jové T et al. Identification of a new integron harboring blaIMP-10 in carbapenem-resistant Acinetobacter baumannii clinical isolates. Antimicrob Agents Chemother 2015; 59:3687–3689 [View Article][PubMed]
    [Google Scholar]
  4. Penteado AP, Castanheira M, Pignatari AC, Guimarães T, Mamizuka EM et al. Dissemination of blaIMP-1-carrying integron In86 among Klebsiella pneumoniae isolates harboring a new trimethoprim resistance gene dfr23. Diagn Microbiol Infect Dis 2009; 63:87–91 [View Article][PubMed]
    [Google Scholar]
  5. Tognim MC, Gales AC, Penteado AP, Silbert S, Sader HS. Dissemination of IMP-1 metallo-β-lactamase-producing Acinetobacter species in a Brazilian teaching hospital. Infect Control Hosp Epidemiol 2006; 27:742–747 [View Article][PubMed]
    [Google Scholar]
  6. Park YK, Jung SI, Park KH, Kim SH, Ko KS. Characteristics of carbapenem-resistant Acinetobacter spp. other than Acinetobacter baumannii in South Korea. Int J Antimicrob Agents 2012; 39:81–85 [View Article][PubMed]
    [Google Scholar]
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